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Biomarkers for detecting anemia factors in patients with anemia

机译:用于检测贫血患者贫血因素的生物标志物

摘要

It is an object of the present invention to provide a method for identifying the cause of anemia as MDS, and in particular, to provide a method for easily identifying MDS, such as not performing bone marrow puncture or requiring the determination of a hematologist. The solution is a method for detecting an anemia factor of an anemic patient including the following steps 1 and 2; (1) a step 1 of measuring the expression level of ACVR2B in polycytic cells contained in peripheral blood obtained from the patient (2) When the expression level of ACVR2B measured in step 1 is greater than the expression level of ACVR2B in the multiblood cells contained in peripheral blood obtained from healthy subjects, the cause of anemia in the patient is MDS Step 2 to determine.
机译:发明内容本发明的目的是提供一种将贫血的原因识别为MDS的方法,尤其是提供一种容易地识别MDS的方法,例如不进行骨髓穿刺或需要血液科医生的确定。该解决方案是一种用于检测贫血患者贫血因素的方法,包括以下步骤1和2; (1)步骤1,测量从患者获得的外周血中所含多核细胞中ACVR2B的表达水平(2)当步骤1中所测量的ACVR2B的表达水平大于所含多血细胞中ACVR2B的表达水平时从健康受试者获得的外周血中,患者贫血的原因由MDS步骤2确定。

著录项

  • 公开/公告号JPWO2014030683A1

    专利类型

  • 公开/公告日2016-07-28

    原文格式PDF

  • 申请/专利权人 国立大学法人九州大学;

    申请/专利号JP20140531657

  • 发明设计人 杉山 大介;

    申请日2013-08-21

  • 分类号G01N33/53;G01N33/574;C07K14/705;

  • 国家 JP

  • 入库时间 2022-08-21 14:40:36

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