首页>
外国专利>
Toxicity prediction method of the compounds according to the cytochrome P450 enzyme metabolic activity pattern
Toxicity prediction method of the compounds according to the cytochrome P450 enzyme metabolic activity pattern
展开▼
机译:根据细胞色素P450酶代谢活性模式预测化合物的毒性
展开▼
页面导航
摘要
著录项
相似文献
摘要
PROBLEM TO BE SOLVED: To predict toxicity about a compound where its toxicity is unknown.;SOLUTION: A method includes analyzing the metabolic pattern of a compound using two or more cytochrome P450's selected from the group consisting of CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2A13, CYP2B6, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2D6, CYP2E1, CYP2J2, CYP2R1, CYP2W1, CYP3A4, CYP3A5, CYP4F2, CYP4F12, CYP4X1, CYP17A1, CYP27A1 and CYP51A1, and predicting the toxicity of the compound, based on the results of the analysis.;COPYRIGHT: (C)2013,JPO&INPIT
展开▼