REGULATORY MACROPHAGES AS A CELL-BASED IMMUNOMODULATORY THERAPY IN PULMONARY HYPERTENSION AND RIGHT VENTRICULAR DYSFUNCTION

摘要

Methods and compositions are provided for preventing and treating pulmonary hypertension (PH) and right ventricular (RV) dysfunction. Aspects of the methods include administering to an individual having PH or at risk of developing PH a cell composition that is enriched for regulatory macrophages (Mregs). Also provided are systems, reagents, and kits that find use in practicing the subject methods.