18F -GLUTATHIONE CONJUGATE AS A PET TRACER FOR IMAGING TUMORS OR NEUROLOGICAL DISORDERS THAT OVEREXPRESS L-PGDS ENZYME

摘要

A PET tracer for imaging tumors or neurological disorders that overexpress L-PGDS enzyme is provided. The present invention have prepared a glutathione conjugate of fluorine-18-labeled fluorobutyl ethacrynic amide using an acceptable amount of radioactivity that is capable of binding to L-PGDS and can be used for in vitro and in vivo imaging studies.