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Composite Carrier for Immobilization of Proteins, Polypeptides or Oligopeptides, Preparation Methods and Application Thereof

机译:固定化蛋白质,多肽或寡肽的复合载体,制备方法和应用

摘要

Provided are a composite carrier for immobilization of a protein, polypeptide or oligopeptide, a preparation method and an application thereof. The composite carrier is a porous material which comprises: (1) a porous organic foam material containing open pores; and (2) a crosslinked product having aldehyde groups and immobilized on the surface of the walls of one or more pores of the porous organic foam material, wherein the aldehyde groups are able to react with the protein, polypeptide or oligopeptide, and the crosslinked product are formed by chitosan via a crosslinking reaction with a polyaldehyde compound.
机译:本发明提供了用于固定蛋白质,多肽或寡肽的复合载体,其制备方法及其应用。所述复合载体是多孔材料,其包括:(1)包含开孔的多孔有机泡沫材料; (2)固定在多孔有机泡沫材料的一个或多个孔的壁的表面上的具有醛基的交联产物,其中该醛基能够与蛋白质,多肽或寡肽反应,并且该交联产物壳聚糖通过与多醛化合物的交联反应而形成。

著录项

  • 公开/公告号US2016168347A1

    专利类型

  • 公开/公告日2016-06-16

    原文格式PDF

  • 申请/专利权人 BIORIGHT WORLDWIDE COMPANY LIMITED;

    申请/专利号US201414902728

  • 发明设计人 CHUNG HONG CHEUNG;JUN WANG;

    申请日2014-07-08

  • 分类号C08J9;C07K17/06;C07K7/62;A01N43/68;B01J31/06;C07K5/083;C07K14/31;C12N11/10;B01J31/02;C07K17/08;C07K1/22;

  • 国家 US

  • 入库时间 2022-08-21 14:38:26

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