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METHOD FOR PREDICTING THE SURVIVAL STATUS AND PROGNOSIS OF ESOPHAGEAL CANCER AND A KIT THEREOF

机译:食管癌生存状况和预后的预测方法及其工具

摘要

The present invention provides a method for determining a survival rate and prognosis state for a patient having esophageal carcinoma, comprising: (a) providing a tissue sample from the patient; (b) measuring a expression level of a target gene in the tissue sample from the patient using reagents specific for the target gene product that are selected from the group consisting of probes, primers, antibodies, and antibody fragments, wherein the expression level is RNA expression, a protein expression at a cellular level or a tissue level; (c) comparing the expression level to a predetermined threshold indicative of a survival rate and prognosis state for the patient; and (d) providing a survival rate and prognosis state for the patient so that care for the patient is able to be determined in accordance with the survival rate and prognosis state, wherein the target gene is peptidase inhibitor 3 (PI3).
机译:本发明提供了一种确定食道癌患者的存活率和预后状态的方法,该方法包括:(a)从该患者提供组织样品; (b)使用对靶基因产物具有特异性的试剂来测量患者组织样品中靶基因的表达水平,所述试剂选自探针,引物,抗体和抗体片段,其中表达水平为RNA表达,在细胞水平或组织水平的蛋白质表达; (c)将表达水平与指示患者的存活率和预后状态的预定阈值进行比较; (d)提供患者的存活率和预后状态,以便能够根据存活率和预后状态确定对患者的护理,其中靶基因是肽酶抑制剂3(PI3)。

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