Method And System For Simultaneous Decomposition Of Multiple Hyperspectral Datasets And Signal Recovery Of Unknown Fluorophores In A Biochemical System

摘要

A system and method are for analyzing fluorescence of fluorophors in an eye using a non-negative matrix factorization (NMF) method. The NMF method may be initialized with Gaussian mixture model fits and may optionally be constrained to provide identical abundance images for data obtained in response to two or more excitation wavelengths.