TREATMENT OF C1013G/CXCR4-ASSOCIATED WALDENSTRÖM'S MACROGLOBULINEMIA WITH AN ANTI-CXCR4 ANTIBODY

摘要

The present disclosure provides a method for treating a subject afflicted with Waldenstrm's macroglobulinemia (WM) comprising administering to the subject a therapeutically effective amount of an antibody or an antigen-binding portion thereof that specifically binds to a CXCR4 receptor expressed on the surface of a WM cell. The disclosure also provides a therapeutic regimen for treating a patient afflicted with C1013G/CXCR4-associated WM.