首页> 外国专利> COMPOSITION FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION COMPRISING LDD175 AS ACTIVE INGREDIENT

COMPOSITION FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION COMPRISING LDD175 AS ACTIVE INGREDIENT

机译:包含LDD175作为有效成分的用于治疗或预防勃起功能障碍的组合物

摘要

The present invention relates to a pharmaceutical composition for treating or preventing erectile dysfunction, containing LDD175 as an active ingredient. Furthermore, the present invention relates to a co-administration preparation for treating or preventing erectile dysfunction, containing LDD175 and a PDE5 inhibitor as active ingredients. The LDD175 of the present invention has an excellent corporal smooth muscle relaxation effect, and thus significantly improved erectile function. Since the LDD175 of the present invention acts on BKCa channels, and thus is expected to have little adverse cardiovascular effects. The LDD175 of the present invention exhibits an erectile dysfunction therapeutic ability equivalent to that of udenafil, which is a PDE5 inhibitor, and showed a synergistic corporal smooth muscle relaxation effect when being co-administered with udenafil.
机译:本发明涉及含有LDD175作为有效成分的治疗或预防勃起功能障碍的药物组合物。此外,本发明涉及包含LDD175和PDE5抑制剂作为有效成分的用于治疗或预防勃起功能障碍的共同给药制剂。本发明的LDD175具有优异的身体平滑肌松弛作用,因此显着改善了勃起功能。由于本发明的LDD175作用于BK Ca 通道,因此预期对心血管的不良影响很小。本发明的LDD175显示出与作为PDE5抑制剂的乌地那非等效的勃起功能障碍治疗能力,并且当与乌地那非共同施用时显示出协同的身体平滑肌松弛作用。

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