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ENHANCED DETECTION OF NON-SOMATIC CIRCULATING NUCLEIC ACIDS
ENHANCED DETECTION OF NON-SOMATIC CIRCULATING NUCLEIC ACIDS
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机译:非体循环核酸的增强检测
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摘要
Methods, equipment and software for the detection of abnormal nucleic acid or fetal nucleic acid sequences circulating in the subjects blood or other body fluids. A scan of a subject's circulating nucleic acid (CNA) is compared to the CNA Data On Normal Healthy Population or to a scan of the subject's own Somatic Nucleic Acid (SNA). Abnormal peaks are identified by subtracting out the “normal” or somatic peaks. The resultant anomalous peaks are compared to anomalous CNA data to identify the abnormalities, or the anomalous peaks of the subjects CNA are isolated, amplified, and sequenced or probed to determine the nature of the anomaly.
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