RAPIDLY-DISSOLVING THIN FILM FORMULATION OF WATER SOLUBLE DIGITALIS GLYCOSIDE FOR THE TREATMENT OF CONGESTIVE HEART DISEASE

摘要

The present invention provides an orally consumable rapidly dissolving solid film comprising: at least one water soluble polymer, and at least one water soluble digitalis glycoside and optionally at least one amorphous cyclodextrin; and wherein the ratio of the at least one water soluble digitalis glycoside to the optionally at least one amorphous cyclodextrin is about 1:1 to about 1:10 and wherein said orally consumable film is adapted to adhere to and dissolve in the mouth of a subject afflicted with heart disease. The present invention also provides methods of making and using the same.