MODULATION OF REGULATORY T CELL FUNCTION VIA PROTEIN KINASE C-eta

摘要

Compounds, uses and methods for modulating an immune response are provided. In particular, modulating the interaction of PKCη with CTLA-4 can modulate an immune response. For example, modulating activity or expression of PKCη, and/or modulating activity or expression of CTLA-4, can be used to modulate interaction of PKCη with CTLA-4, thereby modulating an immune response.