首页> 外国专利> NOVEL COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT

NOVEL COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT

机译:新型化合物,由此制成的药学可接受的盐或光学异构体,其制备方法以及用于预防或治疗包含活性成分的病毒性疾病的药物组合物

摘要

The present invention relates to a novel compound, to a pharmaceutically acceptable salt or optical isomer thereof, to a method for preparing same, and to a pharmaceutical composition for the prevention or treatment of viral diseases containing same as an active ingredient. The novel compound according to the present invention not only has low cytotoxicity but also has excellent antiviral activity against picornavirus such as coxsackievirus, enterovirus, echovirus, poliovirus and rhinovirus, and thus can be effectively used as a pharmaceutical composition for the prevention or treatment of viral diseases such as infantile paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myitis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinus infection, or otitis media.
机译:本发明涉及新型化合物,其药学上可接受的盐或旋光异构体,其制备方法以及用于预防或治疗含有该化合物作为活性成分的病毒性疾病的药物组合物。根据本发明的新型化合物不仅具有低细胞毒性,而且还具有针对小RNA病毒如柯萨奇病毒,肠病毒,回声病毒,脊髓灰质炎病毒和鼻病毒的优异的抗病毒活性,因此可以有效地用作预防或治疗病毒的药物组合物。婴儿麻痹,急性出血性结膜炎,病毒性脑膜炎,手足口病,水疱病,甲型肝炎,心肌炎,心肌炎,胰腺炎,糖尿病,流行性肌痛,脑炎,感冒,疱疹性咽炎,口蹄疫等疾病疾病,哮喘,慢性阻塞性肺疾病,肺炎,鼻窦感染或中耳炎。

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