首页> 外国专利> INHIBITORS OF PLASMODIUM FALCIPARUM EQUILIBRATIVE NUCLEOSIDE TRANSPORTER TYPE I AS ANTI-PARASITIC COMPOUNDS

INHIBITORS OF PLASMODIUM FALCIPARUM EQUILIBRATIVE NUCLEOSIDE TRANSPORTER TYPE I AS ANTI-PARASITIC COMPOUNDS

机译：I型恶性疟原虫平衡核苷转运蛋白的抑制剂作为抗寄生虫化合物

页面导航

摘要
著录项
相似文献

摘要

Inhibitors of Plasmodium falciparum equilibrative nucleoside transporter type 1 are identified and methods of use as anti-parasitic compounds are provided.

机译：鉴定了1型恶性疟原虫平衡核苷转运蛋白的抑制剂，并提供了用作抗寄生虫化合物的方法。

著录项

公开/公告号US2016122362A1

专利类型
公开/公告日2016-05-05

原文格式PDF
申请/专利权人 TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;ALBERT EINSTEIN COLLEGE OF MEDICINE INC.;
展开▼

申请/专利号US201414898846
发明设计人 MYLES AKABAS;ITHIEL JAMES FRAME;DONALD W. LANDRY;ROMAN DENISKIN;SHIXIAN DENG;ALISON RINDERSPACHER;
展开▼

申请日2014-06-26
分类号C07D498/04;C07D239/88;C07D413/14;C07D403/12;C07D417/14;C07D311/16;
国家 US
入库时间 2022-08-21 14:34:58

相似文献

专利
外文文献
中文文献

1. Chalcone analogue as potent anti-malarial compounds against Plasmodium falciparum:Synthesis, biological evaluation, and docking simulation study [J] . Jufrizal Syahri, Emmy Yuanita, Beta Achromi Nurohmah, 亚太热带生物医学杂志（英文版） . 2017,第008期

2. Chalcone analogue as potent anti-malarial compounds against Plasmodium falciparum:Synthesis,biological evaluation,and docking simulation study [J] . Jufrizal Syahri, Emmy Yuanita, Beta Achromi Nurohmah, 亚太热带生物医学杂志：英文版 . 2017,第008期

3. Schistosoma haematobium and Plasmodium falciparum co-infection with protection against Plasmodium falciparum ma-laria in Nigerian children [J] . Nmorsi OPG, Isaac C, Ukwandu NCD, 亚太热带医药杂志（英文版） . 2009,第002期

4. The effects of co-infection with human parvovirus B19 and Plasmodium falciparum on type and degree of anaemia in Ghanaian children [J] . Kwabena Obeng Duedu, Kwamena William Coleman Sagoe, Patrick Ferdinand Ayeh-Kumi, 亚太热带生物医学杂志（英文版） . 2013,第002期

5. Yeast-Based High-Throughput Screen Identifies Plasmodium falciparum Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites [J] . Frame I. J., Deniskin Roman, Rinderspacher Alison, ACS Chemical Biology . 2015,第3期

6. Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1. [J] . Riegelhaupt PM, Cassera MB, Frohlich R Molecular and Biochemical Parasitology . 2010,第1期

7. Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1. [J] . Riegelhaupt PM, Cassera MB, Frohlich R Molecular and Biochemical Parasitology . 2010,第1期

8. Acyclic nucleoside phosphonates as a new class of anti-malarial compounds: Inhibition of Plasmodium falciparum hypoxanthine-guahine-xanthine phosphoribosyltransferase by 9-2-(2-phosphonoethoxy)ethyl-purines and their branched derivatives [C] . Dana Hockova, Antonin Holy, Dianne T. Keough European Symposium on Organic Chemistry . 2009

9. Investigating the role of Plasmodium falciparum equilibrative nucleoside transporter 1 in malarial physiology and anti-malarial activity. [D] . Riegelhaupt, Paul M. 2010

10. Yeast-based High-Throughput Screen Identifies Plasmodium falciparum Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites [O] . I. J. Frame, Roman Deniskin, Alison Rinderspacher, -1

11. Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1 [O] . Paul M. Riegelhaupt, María B. Cassera, Richard F.G. Fröhlich, 2010

1. Binding of Quinoline-Based Inhibitors to iPlasmodium falciparum/iLactate Dehydrogenase: A Molecular Docking Study [J] . Victor F. Waingeh ,Adam T. Groves ,Jeremy A. Eberle . 生物物理学期刊（英文） . 2013,第4期

2. 钠-葡萄糖2型共转运蛋白抑制剂的降糖外作用 [C] . Zhu Chao ,朱超 ,Shao Hua . 2014年中国药学大会暨第十四届中国药师周 . 2014

3. 三磷酸核苷酸转运蛋白调控甘蓝型油菜油脂合成研究 [A] . 李晓 . 2019