Systems, methods, and computer storage media are provided for determining a patient's severity of illness score (pSIS) for a patient admitted to an acute care facility. Data is received corresponding to medical support a patient is receiving from an electronic medical record associated with the patient admitted to an acute care healthcare facility. The data is associated with support variables present in a patient upon admission or administered to the patient within an initial time period from admission. Support variables include both pharmaceutical-type variables and medical device-type variables. Weights are assigned to each support variable associated with the patient. A patient's pSIS is determined by summing the weights. The pSIS accounts for effects that medical support a patient is receiving has on the patient's physiology.
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