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Increased ethanol production by genetic engineering of microorganisms to express hemoglobin

机译:通过微生物基因工程表达血红蛋白提高乙醇产量

摘要

The present disclosure describes novel bacterial strains which express a pyruvate decarboxylase gene and at least one alcohol dehydrogenase gene from a bacteria of the genus Zymomonas and also express a hemoglobin gene from a bacteria of the genus Vitreoscilla. The present disclosure further describes methods for producing fermentation products with a microorganism which expresses a pyruvate decarboxylase gene and at least one alcohol dehydrogenase gene from a bacteria of the genus Zymomonas and also express a hemoglobin gene from a bacteria of the genus Vitreoscilla. Further the present disclosure describes methods for increasing production of a fermentation product comprising genetically engineering a microorganism which expresses a xylose isomerase gene to also express a hemoglobin gene from a bacteria of the genus Vitreoscilla.
机译:本公开内容描述了新颖的细菌菌株,所述菌株从丙酮单胞菌属的细菌表达丙酮酸脱羧酶基因和至少一种醇脱氢酶基因,并且还从玻璃藻属的细菌表达血红蛋白基因。 。本公开进一步描述了用于用微生物生产发酵产物的方法,所述微生物表达丙酮酸脱羧酶基因和至少一种来自发酵单胞菌属的细菌的醇脱氢酶基因,并且还表达来自发酵单胞菌属的细菌的血红蛋白基因。 玻璃藻。另外,本公开内容描述了用于增加发酵产物的生产的方法,所述方法包括对表达木糖异构酶基因的微生物进行基因工程改造,以也表达来自玻璃藻菌属细菌的血红蛋白基因。

著录项

  • 公开/公告号US9309540B2

    专利类型

  • 公开/公告日2016-04-12

    原文格式PDF

  • 申请/专利权人 ILLINOIS INSTITUTE OF TECHNOLOGY;

    申请/专利号US201514720436

  • 发明设计人 TONY SANNY;BENJAMIN C. STARK;

    申请日2015-05-22

  • 分类号C12P7/06;C12N1/22;C07K14/22;C12N9/04;C12N9/02;C12N9/92;

  • 国家 US

  • 入库时间 2022-08-21 14:33:22

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