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METHOD OF ESTABLISHING A GENETIC RISK STRATIFICASTION FOR GENETIC ADDICTION RISK ANALYSIS

机译:建立遗传成瘾风险分析的遗传风险分层的方法

摘要

Methods and kits for assessing severity index for alcohol abuse, drug abuse, and other reward deficiency syndromes. It has been discovered that a multifaceted non-specific RDS behaviors should be considered as the true “reward” phenotype (endophenotype) instead of a single subset RDS behavior such as alcoholism. In an embodiment of the present invention, it has been discovered that there are at least eleven risk alleles associated with ten candidate genes. The methods and kits of the present invention satisfy the need to classify patients at genetic risk for drug/alcohol seeking behavior prior to or upon entry to residential and or non-residential chemical dependency and pain programs.
机译:评估酒精滥用,药物滥用和其他奖赏缺乏综合症的严重程度指数的方法和试剂盒。已经发现,应该将多方面的非特定RDS行为视为真正的“奖励”表型(表型),而不是像酒精中毒那样的单个子集RDS行为。在本发明的一个实施方案中,已经发现与十个候选基因相关的至少十一个风险等位基因。本发明的方法和试剂盒满足了在进入居住和/或非居住的化学依赖性和疼痛程序之前或之后将处于遗传风险中的具有药物/酒精寻求行为遗传风险的患者分类的需要。

著录项

  • 公开/公告号US2016032391A1

    专利类型

  • 公开/公告日2016-02-04

    原文格式PDF

  • 申请/专利权人 SYNAPTAMINE INC.;

    申请/专利号US201514863551

  • 发明设计人 KENNETH BLUM;

    申请日2015-09-24

  • 分类号C12Q1/68;G06F19/22;G06F19/24;

  • 国家 US

  • 入库时间 2022-08-21 14:32:56

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