首页> 外国专利> Thermostabillization of DNA polymerase by protein folding pathway from a hyperthermophile Archaeon, Pyrococcus furiosus

Thermostabillization of DNA polymerase by protein folding pathway from a hyperthermophile Archaeon, Pyrococcus furiosus

机译：嗜热古细菌 Purrococcus furiosus 的蛋白质折叠途径对DNA聚合酶的热稳定作用。

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摘要

The present invention relates to maintaining the activity and stability of enzymes and biologically active proteins at increased temperatures by contacting same with a combination of isolated passive and active chaperones from a hyperthermopilic Archaeon, wherein the chaperones may include heat shock proteins, prefoldin and/or chaperonin proteins. 展开▼

机译：本发明涉及通过使酶和生物活性蛋白与来自超热古菌的分离的被动和主动伴侣的组合接触来维持酶和生物活性蛋白的活性和稳定性，其中所述伴侣可以包括热激蛋白，前折叠蛋白和/或伴侣蛋白。蛋白质。展开▼

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公开/公告号US9416408B2

专利类型

公开/公告日2016-08-16

原文格式PDF

申请/专利权人 FRANK T. ROBB;
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申请/专利号US20060065152

发明设计人 FRANK T. ROBB;
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申请日2006-08-29

分类号C12Q1/68;

国家 US

入库时间 2022-08-21 14:32:33

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2. 一种嗜热古细菌的高活性DNA连接酶突变体 [P] . 中国专利： CN108220255A . 2018-06-29

3. Thermostabillization of Dna Polymerase by Protein Folding Pathway from a Hyperthermophile Archaeon, Pyrococcus Furiosus [P] . 美国专利： US2008318281A1 . 2008-12-25

机译： Dna聚合酶的热稳定通过蛋白质折叠途径从嗜热古菌，激烈热球菌。

4. THERMOSTABLIZATION OF DNA POLYMERASE BY PROTEIN FOLDING PATHWAY FROM A HYPERTHERMOPHILE ARCHAEON, PYROCOCCUS FURIOSUS [P] . CA2662024C . 2011-11-29

机译：超嗜热古菌，焦球菌的蛋白质折叠途径对DNA聚合酶的热稳定作用

5. THERMOSTABLIZATION OF DNA POLYMERASE BY PROTEIN FOLDING PATHWAY FROM A HYPERTHERMOPHILE ARCHAEON, PYROCOCCUS FURIOSUS [P] . 欧洲知识产权局专利： EP1934336B1 . 2009-11-11

机译：超嗜热古菌，焦球菌的蛋白质折叠途径对DNA聚合酶的热稳定作用

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9. Stabilization ofTaq DNA Polymerase at High Temperature by Protein Folding Pathways From a Hyperthermophilic Archaeon,Pyrococcus furiosus [O] . Pongpan Laksanalamai, Andrey R. Pavlov, Alexei I. Slesarev, 2005

10. Characterization of the glycolytic enzyme enolase which is abundant in the hyperthermophilic archaeon, Pyrococcus furiosus [R] . Peak, MJ, Peak, J G, Stevens, F J, 1993

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