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Immunoglobulin cleavage fragments and disease indicators and compositions for detecting and binding such
Immunoglobulin cleavage fragments and disease indicators and compositions for detecting and binding such
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机译:免疫球蛋白裂解片段和疾病指标以及用于检测和结合此类疾病的组合物
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摘要
The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage.
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