A processor-implemented system and method is provided for monitoring patient parameters of engagement plans administered to patients. A builder software application on a first processor-based device is provided for creating an engagement plan from an engagement protocol. An engagement software application on the first processor-based device is configured for monitoring the engagement plan to determine that an administering time for administering the engagement plan has been reached. The engagement software application is further configured for generating a notification message when it is determined that the administering time has been reached. The notification message is transmitted to a registered second processor-based device. The notification message includes an interactive software component for receiving a response message from the second processor-based device. The engagement software application is configured to receive the response message and a status, and to determine patient parameters, thereby engaging patients corresponding to the administered engagement plan.
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