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Extended or continuous wear silicone hydrogel contact lenses for the extended release of comfort molecules
Extended or continuous wear silicone hydrogel contact lenses for the extended release of comfort molecules
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机译:长时间或连续佩戴有机硅水凝胶隐形眼镜,可延长释放舒适分子的时间
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摘要
A drug delivery system is disclosed. The drug delivery system includes a recognitive polymeric hydrogel through which a drug is delivered by contacting biological tissue. The recognitive polymeric hydrogel is formed by using a bio-template, which is a drug or is structurally similar to the drug, functionalized monomers, preferably having complexing sites, and cross-linking monomers, which are copolymerized using a suitable initiator. The complexing sites of the recognitive polymeric hydrogel that is formed preferably mimics receptor sites of a target biological tissue, biological recognition, or biological mechanism of action. The system in accordance with an embodiment of the invention is a contact lens for delivering a drug through contact with an eye.
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