首页> 外国专利> Inhibitors of phosphatidylinositol-3-kinase (PI3) and inducers of nitric oxide (NO)

Inhibitors of phosphatidylinositol-3-kinase (PI3) and inducers of nitric oxide (NO)

机译：磷脂酰肌醇3-激酶（PI3）的抑制剂和一氧化氮的诱导剂（NO）

页面导航

摘要
著录项
相似文献

摘要

The present invention relates to compounds of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.

机译：本发明涉及通过抑制PI3-Akt途径和/或诱导NO来治疗恶性肿瘤的通式1的化合物。本发明还涉及通式1化合物通过抑制PI3-Akt途径和/或诱导NO治疗恶性肿瘤的用途。本发明进一步涉及通过抑制PI3-Akt途径和/或通过向有此需要的哺乳动物施用化合物或所述组合物诱导NO来治疗恶性肿瘤的方法。

著录项

公开/公告号US9290473B2

专利类型
公开/公告日2016-03-22

原文格式PDF
申请/专利权人 SANTU BANDYOPADHYAY;BIKAS CHANDRA PAL;JAISANKAR PARASURAMAN;SIDDHARTHA ROY;JAYASHREE BAGCHI CHAKRABOTRY;INDRANI CHOUDHURY MUKHERJEE;SANJIT KUMAR MAHATO;ADITYA KONAR;SRABANTI RAKSHIT;LABANYA MANDAL;DIPYAMAN GANGULY;KAUSIK PAUL;ANIRBAN MANNA;JAYARAMAN VINAYAGAM;CHURALA PAL;
展开▼

申请/专利号US201013144263
发明设计人 SANTU BANDYOPADHYAY;BIKAS CHANDRA PAL;JAISANKAR PARASURAMAN;SIDDHARTHA ROY;JAYASHREE BAGCHI CHAKRABOTRY;INDRANI CHOUDHURY MUKHERJEE;SANJIT KUMAR MAHATO;ADITYA KONAR;SRABANTI RAKSHIT;LABANYA MANDAL;DIPYAMAN GANGULY;KAUSIK PAUL;ANIRBAN MANNA;JAYARAMAN VINAYAGAM;CHURALA PAL;
展开▼

申请日2010-01-12
分类号A61K31/36;C07C215/54;C07C255/33;C07C39/10;C07D317/06;C07C251/40;C07C251/66;C07C255/36;C07C255/38;
国家 US
入库时间 2022-08-21 14:30:41

相似文献

专利
外文文献
中文文献