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Compositions and methods for diagnosing and treating community-acquired methicillin-resistant Staphylococcus aureus
Compositions and methods for diagnosing and treating community-acquired methicillin-resistant Staphylococcus aureus
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机译:诊断和治疗社区获得性耐甲氧西林金黄色葡萄球菌的组合物和方法 I>
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摘要
The present invention includes compositions and methods for diagnosing and treating CA-MRSA infections in patients. The methods are based on the finding that combining cefoxitin and a synthetic penicillin in a treatment regimen results in a synergistic effect of the two drugs, an effect that is related to PBP4 activity in CA-MRSA isolates. Also provided is a CA-MRSA-specific biomarker which can be used to detect the presence of a CA-MRSA infection in a patient.
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