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Antibody for detecting DNA damage in cells utilizing cell membrane surface antigen Ly6D

机译:利用细胞膜表面抗原Ly6D检测细胞DNA损伤的抗体

摘要

To provide a method for detecting cellular DNA damage by specifically recognizing molecules responsive to DNA strand breaks. A method for detecting DNA damage in cells, which comprises administering in vivo, to cells, an antibody against a cell membrane surface antigen that is expressed in cells undergoing DNA strand breaks to a greater extent than in cells not undergoing DNA strand breaks in an environment that causes DNA damage, and analyzing the expression status of the cell membrane surface antigen.
机译:提供一种通过特异性识别对DNA链断裂敏感的分子来检测细胞DNA损伤的方法。一种检测细胞中DNA损伤的方法,其包括在体内向细胞施用针对细胞膜表面抗原的抗体,所述抗体在经历DNA链断裂的细胞中表达的程度大于在环境中未经历DNA链断裂的细胞中表达的程度。引起DNA损伤,并分析细胞膜表面抗原的表达状态。

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