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Method for the surface treatment of titanium bone implants using, in order, a sodium hydroxide bath and anodization

机译:依次使用氢氧化钠浴和阳极氧化处理钛骨植入物的表面的方法

摘要

The invention relates to a method for the surface treatment of a biologically inert titanium implant to be placed in contact with a bone of the human body, which involves allowing body fluids, such as the inorganic portion of human blood plasma, to naturally deposit, onto the titanium implant, a calcium phosphate film having the formula Ca5(PO4)3(OH), in the form of hydroxyapatite, with a view to rendering the biologically inert titanium biologically active so as to enable the bone to chemically bond to the implant, thus promoting osseointegration, the method including an operation that involves submerging the titanium in a sodium hydroxide (NaOH) solution, wherein said submersion causes the formation of a film of hydrated titanium oxides (HTiO3—) on the titanium, which in turn causes hydroxyl groups (TiOH) to appear, thus enabling the deposition of said calcium phosphate film. The method according to the invention is characterized in that it includes, after the operation of submerging the implant in sodium hydroxide, an operation of anodizing the implant at a given voltage, thereby enabling the stabilization of the oxide film formed by means the operation of submerging the implant in the sodium hydroxide.
机译:本发明涉及一种用于生物惰性钛植入物的表面处理的方法,该植入物被放置成与人体的骨骼接触,该方法涉及使诸如人体血浆的无机部分之类的体液自然沉积到其上。钛植入物,其为羟基磷灰石形式的分子式为Ca 5 (PO 4 3 (OH)的磷酸钙膜,为了使生物惰性钛具有生物活性,从而使骨骼能够化学键合到植入物上,从而促进骨整合,该方法包括将钛浸入氢氧化钠(NaOH)溶液中的操作,其中所述浸入导致在钛上形成水合氧化钛(HTiO 3 -)的膜,继而引起羟基(TiOH)的出现,从而使所述磷酸钙膜得以沉积。根据本发明的方法的特征在于,其包括在将植入物浸没在氢氧化钠中的操作之后,在给定电压下对植入物进行阳极氧化的操作,从而使得通过浸没操作而形成的氧化膜稳定。植入氢氧化钠中。

著录项

  • 公开/公告号US9254351B2

    专利类型

  • 公开/公告日2016-02-09

    原文格式PDF

  • 申请/专利权人 OBL (SOCIÉTÉ ANONYME);

    申请/专利号US201214358033

  • 发明设计人 ALEXANDRE BARBAS;

    申请日2012-11-14

  • 分类号A61L31/16;A61L27/50;C25D11/26;A61L27/06;A61L27/32;

  • 国家 US

  • 入库时间 2022-08-21 14:27:57

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