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Pharmaceutical compositions of ranolazine and dronedarone, method for preparing double-layer Tablet
Pharmaceutical compositions of ranolazine and dronedarone, method for preparing double-layer Tablet
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机译:雷诺嗪和决奈达隆的药物组合物,双层片剂的制备方法
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摘要
A Solid composition comprising a Salt of Phosphoric acid and ranolazine dronedarone spray dried in a Bilayer tablet.Claim 1: a Bilayer Tablet comprising ranolazine and one or more pharmaceutically acceptable excipients in a First layer and a stable Solid formulation of a Salt of Phosphoric Acid by spray dried dronedarone also includes HPMC HPMC E5 and E3 or one or more exci Pharmaceutically acceptable excipients in a second layer.Claim 2: The Bilayer Tablet according to claim 1, wherein the first Layer includes a sustained Release formulation of ranolazine.Claim 7: The Bilayer Tablet according to any one of claims 1 to 6, which includes approximately 200 mg and approximately 1500 mg of ranolazine and between approximately 50 mg and 400 mg roughly equivalent basis of dronedarone for the formulation of a Salt Phosphoric Acid dried by Spraying of dronedarone.
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