tissue targeting complex, use of a tissue targeting complex, method of treating a human or non-human animal body, pharmaceutical composition, and kit

摘要

tissue targeting complex, use of a tissue targeting complex, method of treating a human or non-human animal body, pharmaceutical composition, and, kit. The present invention provides a tissue bleaching complex comprising a tissue bleaching moiety, an octadentated hydroxypyridinone-containing ligand and the ion of an alpha-emitting thorium radionuclide. The invention further provides therapeutic methods utilizing such complexes. methods of their production and use, and kits and pharmaceutical compositions comprising such complexes.