designed peptide-based pcv2 vaccine.

摘要

designed peptide-based pcv2 vaccine. The present invention relates to porcine circovirus (pcv2) vaccine compositions comprising a peptide antigen derived from a pcv2 capsid protein. in various embodiments, the peptide antigen contains capsid protein amino acids from about amino acid 47 to about amino acid 202. in some embodiments, the peptide antigen is optionally linked to an artificial helper epitope and / or mixed with helper epitopes derived from pcv2 orf1 and orf3 proteins. Methods of using pcv2 vaccine compositions are also described. In embodiments, a vaccine composition is used in animals for the prevention of pcv2 infection. in other embodiments, a pcv2 vaccine composition is used with an antigen for the diagnosis of pcv2 infection.