methods to extend progression-free survival used 10-propargil-10-deazaaminopterin

摘要

methods for extending progression-free survival used 10-ptopargil-10-deazaaminopterin. The present invention includes a method for reversing the progressive resistance tendency of consecutive t-cell lymphoma treatments in a patient. this method includes selecting a t-cell lymphoma patient, wherein the patient has had at least one prior t-cell lymphoma treatment, wherein the prior treatment comprises non-10-propargyl-10-deazaaminopterin; and administering to the patient a composition comprising a therapeutically effective amount of 10-propargyl-10-deazaaminopterin, wherein the tendency towards progressive resistance is reversed.