首页> 外国专利> Methods to determine the need for an individual to a cardiac defibrillator implanted (DCI) and to a terrapia antiarrhythmic, to determine the risk of an individual to a cardiu00e1ca sudden death, arrhythmia and heart failure, reduce risk of cardiac death u00fa BITA in an individual, kit, system, and storage medium readable by computer, and,The method implemented by a processor in a computer.

Methods to determine the need for an individual to a cardiac defibrillator implanted (DCI) and to a terrapia antiarrhythmic, to determine the risk of an individual to a cardiu00e1ca sudden death, arrhythmia and heart failure, reduce risk of cardiac death u00fa BITA in an individual, kit, system, and storage medium readable by computer, and,The method implemented by a processor in a computer.

机译:确定个人是否需要植入心脏除颤器(DCI)和抗心律失常性沙门氏菌的方法,以确定个人遭受心脏猝死,心律不齐和心力衰竭的风险,降低心脏死亡的风险在计算机可读的个人,套件,系统和存储介质中,该方法由计算机中的处理器实现。

摘要

Methods to determine the need for an individual to a cardiac defibrillator implanted (DCI) and to a terrapia antiarrhythmic, to determine the risk of an individual to a cardiu00e1ca sudden death, arrhythmia and heart failure, reduce risk of cardiac death u00fa BITA in an individual, kit, system, and storage medium readable by computer, and,The method implemented by a processor in a computer are presented here methods for determine a need of the individual to a cardiac defibrillator implant, methods to determine the risk of the individual to a sudden cardiac death (SCD), arrhythmias, or failure cardu00edac The methods to determine a need of the individual to an anti arrhythmic agent, for example.A sodium channel blocker, and methods to reduce the risk of SCD in an individual.In forms of implementation examples, each method comprises the step of determining a reason, R ~ s ~,That compares a level of a transcribed truncated SCN5A exonn 28 of a biological sample obtained from the individual to (I) a level of a transcribed scnj5a exon 28 full length of the biological sample or (II) a level of all the transcripts SCN5A exon 28 of the biological sample or (III) A level of a transcribed scnj5a exon 28 full-length and one level or one or more transcripts scn5The exon 28 truncated. They are still here with systems, storage media readable by computer, and stored in the same machine readable instructions executable by a processor, and methods related implements for a processor in a computer. Kits are also provided here.
机译:确定个人是否需要植入心脏除颤器(DCI)和抗心律失常性terrapia的方法,以确定个人发生心脏猝死,心律不齐和心力衰竭的风险,降低心脏死亡的风险BITA在此,提出了由计算机中的处理器实现的方法,该方法用于确定个人对心脏除颤器植入物的需求,以及用于确定心脏除颤器风险的方法。个体至心脏性猝死(SCD),心律不齐或衰竭卡的方法确定个体对抗心律不齐药物的需求的方法,例如钠通道阻滞剂和降低患者SCD风险的方法在实现示例的形式中,每种方法都包括确定原因R〜s〜的步骤,该原因比较从个体获得的生物样品的转录的截短SCN5A外显子28的水平(I)生物样本全长转录的scnj5a外显子28的水平或(II)生物样本所有转录本SCN5A外显子28的水平或(III)Scnj5a外显子28转录的水平长度和一级或一个或多个转录本scn5外显子28被截短。它们在这里仍然具有系统,计算机可读的存储介质以及存储在可由处理器执行的同一机器可读指令中的方法,以及与计算机中的处理器相关的实现的方法。这里也提供了套件。

著录项

相似文献

  • 专利
  • 外文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号