methods and compositions for bone and cartilage regeneration by autograft of very small embryonic pluripotent stem cells from adult humans (hvsels)

摘要

The invention provides methods and compositions for the repair or regeneration of osteochondral tissue. The methods and compositions provide an effective amount of isolated differentiable human Very Small Embryonic Like Stem Cells (hVSELs) sufficient for regeneration or repair of an osteochondral tissue. The compositions can be administered directly to the tissue or administered systemically.