Biomaterials for bone grafting, and process for its production

摘要

Biomaterials for bone grafting, and process for its production - biomaterials made from the powder and organic extract of nacre protein of mussel Perna perna combined with alginate, glycerol and water, with the application of biomaterial or as a framework in bone grafting. Initially, the shells (source of nacre) is sanitized in water and neutral detergent.The layer is subjected to the process of particulau00e7u00e3o. The particles are sterilized and placed in an acid solution which obtains a chelating organic extract protein again sterilized. Biomaterials and frameworks are obtained separately, or adding to the particulates or organic extract in distilled water, glycerol and alginates (two or more, in quantities / different ways).The particles are subjected to various physical and chemical assessments. The results show the feasibility of the particulau00e7u00e3o of nacre of shell, and the presence of protein as a constituent of the same, and the extraction protein obtained by dissolving in acetic acid or EDTA.In vitro, presence of organic extract of protein with chloride salts of calcium, sodium phosphate, and sodium bicarbonate suggests a potential application for bone grafting. The framework developed with the organic extract and / or particles of the layer associated with aalginatos, glycerol and water show the application in the area of bony reconstruction.