The process of obtaining and recovery of recombinant bovine papillomavirus VLPs derived from type 2 expressed in mammalian cells and the use of the composition vaccine

摘要

The bovine papillomavirus type 2 recombinant obtained expressed in mammalian cells and the use of vaccine composition.The present invention relates to the production process and recovery of particles similar to virus (virus like particles (VLPs) obtained from the recombinant bovine papillomavirus type 2 (2bovine papillomavirus type 2 - bpv2) produced in mammalian cells inoculated with virus vaccin D recombinant.The technology also is the production of imunu00f3genos based on recombinant VLPs, and the use of these particles for the production of prophylactic vaccine against papillomatosis in cattle and the bovine enzootic haematuria. Finally, the invention comprehends the use of VLPs and composition vacinai for prevention, diagnosis and study of bovine papillomatosis.