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use of bicyclic compound in the manufacture of a composition for relieving or preventing constipation in a constipated human patient and cleaning bowels

机译:双环化合物在制备用于缓解或预防便秘人类患者便秘和清洁肠道的组合物中的用途

摘要

"cathartic composition". It is an object of the present invention to provide an anti-constipation composition containing a halogenated bicyclic compound as an active ingredient in a bicyclic / monocyclic structure ratio of at least 1: 1. The halogenated bicyclic compound is represented by formula (I): where x1- and x2- are preferably both fluorine atoms. The composition can be used to treat constipation without substantive side effects, such as an upset stomach.
机译:“导泻成分”。本发明的目的是提供一种抗便秘组合物,其包含以双环/单环结构比为至少1∶1的卤代双环化合物作为活性成分。卤代双环化合物由式(I)表示:其中x 1和x 2优选都是氟原子。该组合物可以用于治疗便秘而没有实质性副作用,例如胃部不适。

著录项

  • 公开/公告号BRPI0114042B1

    专利类型

  • 公开/公告日2016-11-08

    原文格式PDF

  • 申请/专利权人 SUCAMPO AG;

    申请/专利号BR20010114042

  • 发明设计人 RYUJI UENO;

    申请日2001-09-04

  • 分类号A61K31/335;C07D311/94;A61K31/23;A61K31/35;A61K31/352;A61K31/4741;A61K31/557;A61K31/5575;A61K31/558;A61P1;A61P1/10;

  • 国家 BR

  • 入库时间 2022-08-21 14:26:58

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