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oily pharmaceutical composition and use of peroxidized lipids

机译:油性药物组合物和过氧化脂质的用途

摘要

The present invention relates to a peroxidized lipid and silica oily pharmaceutical composition characterized in that it contains, as essential constituents, peroxidated lipids having a peroxidation rate of 5%. and 600 milliequivalents per kilo and silica dispersed in said peroxidized lipids at a concentration of greater than or equal to 0.5 wt% and less than 4 wt% relative to the weight of said composition. In this composition, the peroxidated lipids are preferably obtained by peroxidation of a natural vegetable oil and the silica is preferably colloidal silica. The present invention further relates to the use of the composition for the manufacture of a pharmaceutical composition for the treatment of xerostomia.
机译:本发明涉及过氧化脂质和硅油状药物组合物,其特征在于它含有过氧化率为5%的过氧化脂质作为基本成分。相对于所述组合物的重量,二氧化硅以每公斤600毫当量的量分散在所述过氧化脂质中,并且浓度大于或等于0.5重量%且小于4重量%。在该组合物中,过氧化脂质优选通过天然植物油的过氧化获得,并且二氧化硅优选为胶体二氧化硅。本发明进一步涉及该组合物在制备用于治疗口干症的药物组合物中的用途。

著录项

  • 公开/公告号BRPI0317196B1

    专利类型

  • 公开/公告日2016-09-27

    原文格式PDF

  • 申请/专利权人 LABORATOIRES CARILENE;

    申请/专利号BR20030317196

  • 发明设计人 STÉPHANE DESJONQUERES;

    申请日2003-12-22

  • 分类号A61K9;A61K31/23;A61K31/231;A61K31/695;A61K36/185;A61K36/286;A61K36/48;A61K36/736;A61K36/87;A61K36/899;A61P1/02;

  • 国家 BR

  • 入库时间 2022-08-21 14:26:58

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