compound, hydrobromide, hydrochloride, methanesulfonate, ethane-1,2-disulfonate, hsp90 inhibitor, agent for inhibiting hsp90 atpase activity, agent for inhibiting hsp90 binding in atp, medicine, anticancer agent, pharmaceutical composition, method for treat cancer, and use of a compound.

摘要

"compound, hydrobromide, hydrochloride, methanesulfonate, ethane-1,2-disulfonate, hsp9o inhibitor, agent to inhibit hsp9o atpase activity, agent to inhibit hsp9o binding to atp, drug, anticancer agent, pharmaceutical composition, method for treating cancer, and use of a compound "is disclosed a novel compound that inhibits an hsp9o activity, in particular a novel compound that inhibits an hsp9o function as a chaperone protein and has an antitumor activity. Specifically disclosed are: a pyrazolopyrimidine compound represented by formula (1) having various substituents, which inhibits an hsp9o atpase activity and has an antitumor activity; an hsp9o inhibitor containing a compound represented by formula (1); a pharmaceutical formulation containing a compound represented by formula (1); an antitumor agent containing a compound represented by formula (1); a pharmaceutical composition containing a compound represented by formula (1); and a method of treating cancer in which a compound represented by formula (1) is used.