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cyclic peptide, pharmaceutical composition, and methods for treating a disease, disorder and / or condition, and for reducing food intake, body weight and / or body weight gain.
cyclic peptide, pharmaceutical composition, and methods for treating a disease, disorder and / or condition, and for reducing food intake, body weight and / or body weight gain.
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机译:环肽,药物组合物和用于治疗疾病,病症和/或病状以及减少食物摄入,体重和/或体重增加的方法。
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摘要
The invention relates to melanocortin receptor-specific cyclic peptides of Formula (I) or a pharmaceutically acceptable salt thereof, where R1, R2, R3, R4a, R4b, R4c, R5, x and y are as defined in the specification. These compounds are particularly useful in the treatments of energy homeostasis and metabolism related (e.g. diabetes), food intake related and/or energy balance and body weight related diseases, disorders and/or conditions, including obesity, overweight and diseases, disorders and/or conditions associated with obesity and/or overweight, such as type 2 diabetes and metabolic syndrome.
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