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Vaccine therapy for choroidal neovascularization

机译:脉络膜新生血管的疫苗治疗

摘要

The present invention provides novel pharmaceutical agents and methods for treating or preventing diseases caused by neovascularization in human choroid (neovascular maculopathy). The present invention provides pharmaceutical compositions and vaccines for treating and/or preventing diseases caused by neovascularization in human choroid (neovascular maculopathy), comprising at least one type each of a peptide comprising an amino acid sequence derived from a VEGFR-1 protein and having an activity of inducing cytotoxic T cells, and a peptide comprising an amino acid sequence derived from a VEGFR-2 protein and having an activity of inducing cytotoxic T cells.
机译:本发明提供了用于治疗或预防由人脉络膜的新血管形成引起的疾病的新药物和方法(血管性黄斑病)。本发明提供了用于治疗和/或预防由人脉络膜的新血管形成引起的疾病(血管性黄斑病)的药物组合物和疫苗,其包含至少一种每种肽,所述肽包含衍生自VEGFR-1蛋白的氨基酸序列并且具有具有诱导细胞毒性T细胞的活性的肽,和包含衍生自VEGFR-2蛋白的氨基酸序列并具有诱导细胞毒性T细胞的活性的肽。

著录项

  • 公开/公告号BRPI1013025A2

    专利类型

  • 公开/公告日2016-04-05

    原文格式PDF

  • 申请/专利权人 ONCOTHERAPY SCIENCE INC.;

    申请/专利号BR2010PI13025

  • 申请日2010-06-10

  • 分类号A61K38;A61K39;A61P9;A61P27/02;A61P35;C07K14/71;C12N15/09;

  • 国家 BR

  • 入库时间 2022-08-21 14:26:40

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