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Method for obtaining extract, compound and composition having inhibitory activity of Haemonchus contortus proteases

机译:具有捻转血矛线虫蛋白酶抑制活性的提取物,化合物和组合物的获得方法

摘要

Method for obtaining extract, compound and composition having inhibitory activity of Haemonchus contortus proteases. The present invention relates to an active fraction of an extract of plants of the genus apolar maprounea as well, one or more compounds isolated from the extract which has inhibiting activity of Haemonchus corztortus proteases.The present invention also refers to a method for obtaining the active fraction of active compounds and composition comprising said fraction or so-called compostos.mais specifically the active fraction of this invention is obtained from the extract of maprounea hexu00e2nico guicmensis.The present invention also refers to the use of this fraction or these compounds in the formulation of a composition for the treatment of animals infected with Haemonchus corztortus.More particularly, the present invention relates to a method for obtaining a mixture of E - ferulatos, particularly and ferulatos of dodecosila (1), tetracosila (2), hexacosila (3), octacosila (4), (5), which have triacontila inhibitory activity of Haemonchus conforms proteases.The invention has great applicability to the livestock industry and for the goats of subsistence avoiding losses. For oscriadores.
机译:获得具有捻转血矛线虫蛋白酶抑制活性的提取物,化合物和组合物的方法。本发明还涉及非极子红松属植物的提取物的活性级分,从该提取物中分离的一种或多种具有抑制Haemonchus corztortus蛋白酶活性的化合物。本发明还涉及获得该活性剂的方法。活性化合物的馏分和包含所述馏分或所谓的堆肥的组合物,特别地,本发明的活性馏分从枫香枫木提取物中获得。本发明还涉及该馏分或这些化合物在制备中的用途。更具体地,本发明涉及一种用于获得E-阿魏酸盐,特别是十二指肠(1),四草(2),六草( 3),具有金丝桃属素对蛋白酶的三线抑素抑制作用的八角茴香(4),(5)。适用于畜牧业和维持生计的山羊避免损失。对于oscriadores。

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