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carbohydrate derivative, pharmaceutical composition and use of the carbohydrate derivative

机译:碳水化合物衍生物,药物组合物和该碳水化合物衍生物的用途

摘要

"carbohydrate derivative, pharmaceutical composition and use of the derivative". The invention relates to a carbohydrate derivative having the formula I wherein R1 is C1-4 alkoxy; R ^ 2 ^, R ^ 3 ^ and R ^ 4 ^ are independently C 1-4-alkoxy or oso-3-R -; the total number of sulfate groups is 4, 5 or 6 and the twisted lines represent bonds either above or below the plane of the six membered ring to which they are attached; or a pharmaceutically acceptable salt thereof. The compounds of the invention have antithrombotic activity and may be used in the treatment or prevention of thrombosis and for inhibition of smooth muscle cell proliferation.
机译:“碳水化合物衍生物,药物组合物及其用途”。本发明涉及具有式I的碳水化合物衍生物,其中R 1是C 1-4烷氧基。 R ^ 2 ^,R ^ 3 ^和R ^ 4 ^独立地为C 1-4-烷氧基或oso-3-R-;硫酸根基团的总数为4、5或6,并且虚线表示与它们相连的六元环的平面之上或之下的键;或其药学上可接受的盐。本发明的化合物具有抗血栓形成活性,可用于治疗或预防血栓形成和抑制平滑肌细胞增殖。

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