首页> 外国专利> The dosage of alpha___ lambda_ alpha toys and___ alpha___CK2 as therapeutic drugs was at alpha__uuuuuuuuuuuuuuuuuu

The dosage of alpha___ lambda_ alpha toys and___ alpha___CK2 as therapeutic drugs was at alpha__uuuuuuuuuuuuuuuuuu

机译:alpha___ lambda_ alpha玩具和____ alpha __ CK2作为治疗药物的剂量为alpha__uuuuuuuuuuuuuuuuuuu

摘要

The invention relates to a pharmaceutical composition comprising a peptide inhibitor (P54 for short) kappa alpha e_kinase 2 (CK2) and a typical colonel. The drug is used for cancer treatment and granted together, individually or in sequence.These include the chemotherapeutic drugs cisplatin, _alpha_, vinblastine, 5-fluorouracil, adriamycin, cyclophosphamide, etoposide, mitomycin C, _mu alpha_ It is also known as Velcade.The synergistic effect of peptides and P54 in the combination of anticancer drugs at effective concentrations of each kappa__alpha_alpha_____ One is from 10 to 100 times less than every drug that inhibits cell growth.Compared with the present invention, the combination shows low toxicity anticancer theta e The rest represent an important advantage, therefore, in the use of tumor therapy.However, the resistance to P54_induced by the combination of the precursor and the sequential administration of the drug Gamma kappa Omega therapy for cancer.
机译:本发明涉及药物组合物,其包含肽抑制剂(简称P54)κα激酶2(CK2)和典型的上校。该药物用于癌症治疗,可单独或依次给予治疗,包括化疗药物顺铂,α,长春碱,5-氟尿嘧啶,阿霉素,环磷酰胺,依托泊苷,丝裂霉素C,μα,也称为Velcade。在每种kappa_alpha_alpha_____有效浓度的抗癌药物组合中,肽和P54的协同作用是每种抑制细胞生长的药物的10到100倍。与本发明相比,该组合显示出低毒性的抗癌理论。因此,在肿瘤疗法的使用中具有重要的优势。然而,前体药物的结合和顺序给予Gamma kappa Omega治疗癌症可诱导对P54_的抵抗。

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