Apremilast solid form and process for preparing thereof

摘要

Solution relates apremilastu solvate with tetrahydrofuran (THF) of formula II, wherein the molar ratio apremilastu and THF is 2: 1st Apremilastu THF solvate exhibits a characteristic melting temperature of 79.4 degC. Another solution is a method of preparing THF solvate apremilastu and also pharmaceutical compositions containing THF solvate apremilastu and at least one pharmaceutically acceptable excipient selected from a number of lactose, microcrystalline cellulose, croscarmellose sodium, magnesium stearate.