METHODS OF PREVENTION AND / OR TREATMENT OF CARDIOMYOPATHY AND ELIMINATION OF CARDIOMYOPATHY SYMPTOMS, PHARMACEUTICAL COMPOSITION, VECTORS

摘要

The present invention relates to a method for the prevention or treatment of cardiomyopathy due to energy deficiency in a subject in need thereof, said method comprising administering to said subject a therapeutically effective amount of a vector containing the nucleotide sequence of a gene capable of restoring energy deficiency. In more detail, the present invention relates to a method of preventing or treating cardiomyopathy associated with Friedreich's ataxia in a subject in need thereof, said method comprising administering to said subject a therapeutically effective amount of a vector containing the nucleotide sequence encoding frataxin (FXN).