SOLUTIONS TO IMPROVE STABILITY AND LIFE OF SOLUTION FOR CONSERVING BODIES AND FABRICS

摘要

Disclosed solutions for preserving organs and tissues with improved stability. Solutions consist of two separate solutions. The first solution, solution A, consists of a balanced salt solution that is stable in solution at a pH of 7.0 or higher. The second solution, solution B, consists of an aqueous solution containing L-glutathione and / or cysteinyl-glycine, sugar, such as D-glucose, L-arginine, a reducing agent, such as ascorbic acid, and water at a pH below 7.0 preferably from about 3.0 to 5.0. The two solutions are then mixed together immediately prior to use, and the pH is adjusted to approximately 7.3, resulting in a solution for the preservation of organs and tissues, which has improved stability. Preferably, solution A has a pH of approximately 7.6, and solution B has a pH of approximately 5.0. The present invention also includes kits 20, which contain two solutions in two separate containers 22, 24. In an alternative embodiment, solution A may be sugar.