Stable α-crystal form of imatinib mesylate and process for preparation there of

摘要

The invention relates to stable, free flowing and non-hygroscopic a-crystalline form of methane sulfonic acid salt of 4-(4-methyl piperazin-1-yl methyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-yl amino)phenyl]-benzamide (imatinib mesylate). A process for the preparation of the a-crystal polymorph is also described.