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Inhibition of factor b, the alternative complement pathway and methods related thereto
Inhibition of factor b, the alternative complement pathway and methods related thereto
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机译:因子b的抑制,替代补体途径及其相关方法
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摘要
Disclosed are novel inhibitors of the alternative complement pathway and particularly, novel anti-factor B antibodies. Also disclosed is the use of such inhibitors to reduce or prevent airway hyperresponsiveness and/or airway inflammation by selectively inhibiting the alternative complement pathway, thereby treating diseases in which such conditions play a role. Also disclosed is the use of such inhibitors to reduce or prevent other diseases and conditions, including ischemia-reperfusion injury, by inhibition of the alternative complement pathway.
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