A process for identification of biomarkers for keratoconus progression

摘要

The present invention relates to a process of identification of biomarkers for disease progression of Keratoconus, a corneal thinning disorder. Proteomic profile of the KC patient tear was analyzed to identify up and down regulated proteins, compared to control and the proteins that indicated association with clinical grades were considered as biomarkers for KC progression. The biomarkers are used in form of diagnostic kit for detection of Keratoconus disease.