A system and method for optimized computation fluid dynamics (CFD) mesh generation are disclosed. In one embodiment, a CFD mesh for a vehicle is formed based on a first set of mesh generation parameters. Flow properties are then computed by performing a CFD simulation on the formed CFD mesh. An attachment line of a component of interest of the vehicle is then located. A span wise variation in flow properties substantially around a region of interest on the located attachment line is then determined. The span wise variation in the flow properties is then compared to a threshold variation value. The above steps are then repeated using a next set of mesh generation parameters to form an optimized CFD mesh based on the outcome of the comparison until the determined span wise variation is less than or equal to the threshold variation value. [FIG. 2]
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