ANTI FIBROTIC PEPTIDES AND THEIR USE IN METHODS FOR TREATING DISEASES AND DISORDERS CHARACTERIZED BY FIBROSIS

摘要

The invention provides methods and compositions for inhibiting and/or reversing fibrosis. The invention further provides pept ides and polypeptides which are BMP agonists which trigger BMP signaling and inhibit and/or reverse EMT in a cell or tissue. In partic ular embodiments the BMP agonist peptides of the invention can include peptides having amino acid sequences selected from the group consisting of SEQ ID NOs: 1 77.