Tissue transplantation involving and tissues modified by decellularization and recellularization of donor tissues for minimized or obviated rejection reactions

摘要

A kidney was removed from a donor animal (a pig) and was later transplanted into a recipient animal (another non familial pig). The procedure produced a functioning kidney (actively producing urine) in the recipient without rejection or the formation of scar tissue after two weeks post transplantation. The procedure involves decellularization of the donor organ followed by recellularizing the donor organ with cells grown from the recipient s stem cells through use of cytokines or "growth factors" that are extracted from the recipient s blood plasma.